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KMID : 1231220150060020065
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Journal of the Korean Society for Research on Nicotine and Tobacco
2015 Volume.6 No. 2 p.65 ~ p.70
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How to Choose the Medications for Treating Nicotine Dependence?
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Kim Yun-Hee
Baek Yu-jin
Lee Eun-Young
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Abstract
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Several drugs and medications are in some way related to or used in the treatment of smoking cessation. The first line therapies for the treatment of nicotine dependence are nicotine replacement therapy (NRT), bupropion or varenicline. Various types of NRT are available such as patches, gums or lozenges. Theses medications can help with the craving for tobacco and withdrawal symptoms. Bupropion and varenicline work in a different way than nicotine replacement therapy. Bupropion may be used to delay weight gain shortly after smoking cessation among those who are afraid of weight gain or for people with depressive mood. Varenicline is the most effective drug when used as a single therapy. It works in the brain to reduce the physical effects of nicotine, However, this may have several serious reactions such as mental change or cardiovascular side effects which need close monitoring. Combination therapy of these medications can be applied to smokers who have failed previous cessation attempts.
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KEYWORD
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Smoking cessation, Nicotine dependence, Nicotine replacement therapy, Bupropion, Varenicline
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